PhD Candidate (m/f/d) Neurohomeostasis – Department ofPsychiatry and Psychotherapy

The University Hospital Bonn (UKB) is a maximum care
hospital with more than 1,300 beds. Our more than 9,000 employees
take on tasks in research, teaching and patient care as well as in
public health at the highest level. In the science ranking (LOMV)
and in the economic result, the UKB is number 1 of the university
hospitals in NRW and in 2021 had the third highest case mix index
of the university hospitals in Germany. The following 65% part-time
position is to be filled by September 1st 2025 in the research
group Neurohomeostasis, Department of Psychiatry and Psychotherapy
of the University Hospital Bonn:PhD Candidate (m/f/d) Due to third
party funding, the position is limited to 2 years due the project.
Additional 2 years will be covered by a partner institution. Our
research focuses on understanding the intricate links between
stress, proteostasis, and cellular function, aiming to identify
promising therapeutic targets for the treatment of neuropsychiatric
disorders. Taking a multidisciplinary and translational approach,
we combine cell models, animal experiments, and human studies with
protein biochemistry, pharmacology (e.g. autophagy induction, GLP-1
agonists), and advanced multi-omics techniques. The offered project
aims to unravel the interplay between metabolic and psychiatric
phenotypes by establishing cellular autophagy as a central
mechanism linking bi-directional brain-body interactions in
stress-related disorders. Analyses of the autophagic pathway along
with plasma proteomics and metabolomic polyamine profiling will be
performed from human and murine samples. Tasks:Conduct experimental
research using advanced molecular and cellular biology
techniquesAnalyze and interpret complex biological data to
contribute to groundbreaking discoveriesCollaborate with
interdisciplinary teams and engage in scientific discussionsPresent
findings at conferences and contribute to high-impact
publicationsAssist in teaching and mentoring students in the
research groupRequirements:Master’s degree in a relevant field,
e.g., Biology, Biomedical Sciences, BiochemistryStrong background
in cell signaling, proteostasis, and autophagy
mechanismsFamiliarity with statistical methods, data analysis, and
omics data interpretationHighly motivated, curious, and eager to
contribute to scientific advancementsExcellent communication and
teamwork skillsFluency in English, both spoken and writtenWe
offer:Responsible and versatile: a job with a lot of creative
freedom in a collegial teamSecure in the future: fee according to
TV-L EG13Flexible for families: flexible working time models, the
option of a place in the company day-care center and offers for
those returning from parental leaveProvision for later: company
pension schemeClever to work: possibility of an interest-free loan
to buy an e-bikeTailor-made education: subsidized further education
and trainingSystematic start: structured inductionHealthy at work:
numerous health promotion offers, free membership in UKBfitEmployer
benefits: preferential offers for employees (corporate benefits)We
are committed to diversity and equal opportunities. Our goal is to
increase the proportion of women in areas where women are
underrepresented and to particularly promote their careers. We
therefore urge relevantly qualified women to apply. Applications
are treated in accordance with the State Equal Opportunities Act.
Applications from suitable people with proven severe disabilities
and those of equal status are particularly welcome.How to apply:Do
you meet our requirements and are you looking for a varied and
challenging job? Do not hesitate and send your detailed application
(preferably by e-mail in one file up to 5 MB in size) by June 18th
2025, stating the job advertisement number ST-23056 to: Patricia
Schikorra RG Neurohomeostasis Department of Psychiatry and
Psychotherapy Universitätsklinikum Bonn Venusberg-Campus 1 53127
Bonn E-Mail:
patricia.schikorra@ukbonn.dewww.ukbonn.de