PhD Candidate in Translational Pancreatitis and Thromboinflammation Research; part time 65 (m/w/d)

Scope of duties

· Work on the Collaborative Research Centre project (SFB) “Thromboinflammatory mechanisms of pancreatitis progression and associated splanchnic and portal vein thrombosis”
· Investigate cellular and molecular mechanisms that link pancreatic inflammation, coagulation and thrombotic complications
· Study the role of platelet–neutrophil interactions and sphingolipid metabolism in acute and acute-on-chronic pancreatitis
· Plan and perform experimental studies using cellular systems, patient-derived biosamples and established preclinical models of pancreatitis
· Apply modern molecular, biochemical and cell biological methods, including cell culture, flow cytometry, immunofluorescence microscopy, RNA and protein analysis and functional cellular assays
· Contribute to the characterization of inflammatory, thrombotic and metabolic pathways using proteomic, lipidomic or transcriptomic approaches
· Participate in the development and validation of targeted therapeutic strategies, including nanoparticle- and aptamer-based delivery approaches
· Quantitatively analyze, interpret and document experimental and clinical research data
· Collaborate closely with scientists, clinicians and technology platforms within the interdisciplinary Collaborative Research Centre
· Present research findings at internal meetings and national and international scientific conferences and contribute to scientific publications

Our requirements

· A successfully completed university degree, preferably a Master’s degree or equivalent, in biology, biochemistry, molecular medicine, biotechnology, pharmacy or a related life-science discipline
· Strong interest in translational research, inflammation, pancreatitis, vascular biology or immunology
· Practical experience in molecular and cell biology, for example mammalian cell culture, flow cytometry, microscopy, immunoblotting, quantitative PCR or functional cellular assays
· Previous experience with primary cells, patient samples, animal models, proteomics, lipidomics, nanoparticles or drug-delivery systems is an advantage, but not mandatory
· Motivation to learn new experimental technologies and quantitative analysis methods
· A careful, structured and reliable approach to experimental work
· Scientific curiosity, high motivation and the ability to work both independently and as part of a team
· Strong communication skills and enthusiasm for working in an interdisciplinary and international research environment
· Very good written and spoken English
· German language skills are not required

Our offer

· An innovative PhD project within an interdisciplinary Collaborative Research Centre at LMU University Hospital

· A translational research environment combining experimental pancreatitis research, vascular biology, immunology and clinical medicine
· The opportunity to work with patient-derived biosamples, established disease models and modern molecular and imaging technologies
· State-of-the-art laboratories and access to advanced flow cytometry, microscopy, proteomics, lipidomics and data-analysis platforms
· Close collaboration with basic scientists, clinician scientists, bioinformaticians and experts in vascular and inflammatory biology
· Integration into a highly collaborative national research network with opportunities for scientific exchange across several disciplines
· Structured scientific supervision and support for professional and personal development
· Opportunities to participate in scientific workshops, training programmes and national and international conferences
· A supportive and inspiring working environment that encourages scientific independence and the development of new ideas
· Employment according to the German public-sector collective agreement, including annual leave and additional benefits in accordance with the applicable regulations
· The position is initially limited to three years. The precise wording regarding a possible extension should be adapted to the SFB funding conditions
· The position is based at LMU University Hospital, Campus Großhadern, in Munich
· Remuneration is based on the Collective Agreement for the Public Sector of the Länder (TV-L) including all allowances customary in the public sector.